Abstract Antimicrobial peptides (AMPs) are peptide antibiotics with a broad spectrum of antimicrobial activities.Activity prediction of AMPs from their amino acid sequences is of great therapeutic importance but imposes challenges on prediction methods due to label interactions.In this paper we propose a novel multi-label learning model to address
In the present study, we attempted to control the pH profile of the catalytic activity of the industrially relevant alkaline protease KP-43, by incorporating 3-nitro-l-tyrosine and 3-chloro-l-tyrosine at and near the catalytic site.Thirty KP-43 variants containing these non-natural amino acids at the specific positions were synthesized in Escherich
Simultaneous Localisation and Mapping (SLAM) is one of the fundamental problems in autonomous mobile robots where a robot needs to reconstruct a previously unseen environment while simultaneously localising itself with respect to the map.In particular, Visual-SLAM uses various sensors from the mobile robot for collecting and sensing a representatio
At the end of 2015, Europe faced a unique phenomenon in modern history - the explosive nature of migration processes.Mass of internally displaced persons and economic migrants from the Middle East are aggressively trying to become flamin fury peach full residents, attracted by the image of Europe as an oasis of prosperity, democracy and human right
Objective(s): Although 70 x 70 tablecloth tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) can selectively induce apoptosis in tumor cells, more than half of tumors including non-small cell lung cancer (NSCLC) exhibit TRAIL-resistance.The purpose of this study was to determine whether subtoxic-dose cisplatin and TRAIL could synergist